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In response to the changing regulatory climate, tobacco firms are exploring new ways to promote their products.[3] Firms have dramatically changed their expenditure patterns, and have shifted their focus towards spending on traditional print advertisements and promotional activities instead of television and radio ads

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While early cross-sectional studies yielded inconsistent results regarding this association [55,56,57], more robust prospective longitudinal cohort studies have provided compelling evidence

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It is perhaps natural that efforts should be made to discredit evidence which suggests a different view. Though Fisher was in the minority, he was not alone in taking this different view. Joseph Berkson, the chief statistician at the Mayo Clinic throughout the 1940s and 50s, was also a prominent skeptic on the smoking-cancer question, as was Charles Cameron, president of the American Cancer Society