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These were particularly common in period movies like Sherlock Holmes: Game of Shadows and Midnight in Paris (both rated PG-13, both of which had more than 50 tobacco incidents)

There are at least three possibilities: Over this period, cigarettes have been reformulated in ways that might make them more dangerous

Signs & Clinical Presentation Watch for persistent combinations of: Painless jaundice , dark urine, pale stools Upper abdominal or back pain Unintended weight loss , poor appetite, nausea New-onset diabetes or worsened glycaemic control (India: even after 40 merits attention when paired with weight loss) Diagnostic Approaches Typical pathway: Pancreas-protocol CT and/or MRI/MRCP EUS-guided FNA (tissue diagnosis) when needed CA 19-9 : helpful for monitoring/prognosis , not population screening Treatment Modalities Curative / Surgical Whipple (pancreaticoduodenectomy) for head lesions

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Experienced smokers, on the other hand, may feel comfortable dipping into full-bodied cigars