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Smokers have a greater susceptibility towards certain kinds of infections

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Increased pain perception associated with nicotine withdrawal may involve changes in peripheral and central nervous system reactions (sensitization), endogenous opioid release, and hypothalamicpituitaryadrenal (HPA) axis regulation [11]

Smokeless tobacco (SLT) and cancer mortality Eight studies providing 19 individual estimates for mortality due to various cancers were retrieved for this review (Table III)80,81,82,83,84,85,86,87