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Moreover, in THC- a group it is required to increase the opioid daily use by 63% to achieve the same pain relief as the THC+ group (Pawasarat et al
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Like THC, CBD exhibits low oral bioavailability (around 6%) due to extensive first-pass metabolism, while its inhalation bioavailability ranges from 11-45% (40)

Manila:World Health Organization Regional Office for the Western Pacific
