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And, in that case, the product would be subject to the safety and efficacy standard: the company must provide the required data, which includes the results from two adequate and well-controlled trials

demonstrated increased epithelial-mesenchymal transition (EMT) in A549 CCL-185 lung cancer cells, with resultant increased invasive/metastatic potential, on exposure to various flavored ELs including menthol based [120]

Such a measure would be a world first, and is supported by extensive research evidence in Canada and internationally

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There has been no deviation to that trend since plain packs were introduced." The UK government is currently considering whether to follow Australia's lead on plain packaging