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Circulation 144, e472-e487, (2021)
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Zhu et al .39 utilized 2-D gel electrophoresis and MALDI-TOF-MS analysis to screen the different expressed proteins in mice epididymis treated with tobacco smoking and identified 27 proteins which show significant alterations in protein profile
Nicotine pouches first came on the European market around 2009 and began a gradual rollout in American markets five years later before becoming broadly available in the US in 2019
