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Smokers are at greater risk for diseases that affect the heart and blood vessels (cardiovascular disease).1,2 Smoking causes stroke and coronary heart disease, which are among the leading causes of death in the United States.1,3 Even people who smoke fewer than five cigarettes a day can have early signs of cardiovascular disease.1 Smoking damages blood vessels and can make them thicken and grow narrower

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9 Inhibition of SMPD3 ameliorates nicotine-induced NASH