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These findings support our initial studies with TLR KO mice and suggest downstream signaling, specifically the MyD88/NF-B pathway is essential in COPD-driven K-ras mutant lung cancer promotion

Establishing a Nicotine Threshold for Addiction The Implications for Tobacco Regulation. New England Journal of Medicine 331(2): 123125

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The report notes that addressing disparities requires reflection on the complex history of the commercialization of tobacco and both past and present-day experiences of racism, discrimination, and targeted marketing by the tobacco industry

Airway epithelium is the first line of defense against inhaling particles and pathogens due to its barrier property, which plays a crucial role in regulating innate barrier immunity and maintaining homeostasis [7]