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The researchers found that during this period: There was an overall increase in the number of people who succeeded in quitting smoking There was a substantial increase in the number of people who used e-cigarettes during this period, from a negligible use in 2006 to 21.3% at the end of the study The number of people who used e-cigarettes to quit smoking increased from a negligible number in 2006 to 35% in early 2015 The use of nicotine replacement therapy reduced slowly Thus, based on the above data, the researchers suggest that e-cigarettes could have played a role in helping people quit smoking

Office of the Surgeon General

Acknowledgements The authors gratefully acknowledge the comments made by the reviewers as well as the editor on earlier versions of this manuscript

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