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SNRIs: The Interaction with Cannabis Serotonin-norepinephrine reuptake inhibitors (SNRIs), such as Effexor XR and duloxetine (Cymbalta), increase levels of serotonin and norepinephrine in the brain

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[DOI] [PMC free article] [PubMed] [Google Scholar] 140

In 2009, Cohen et al., also reported on the exposure of epithelia cell cultures to the particulate phase of cigarette smoke reducing cilliary beat increase when stimulated.13 Besides in vitro evidence, the exposure to cigarette smoke also harms mucociliary transport in humans, both in acute exposure14 as well as in its chronic counterpart.15,16 Cigarette smoking is also associated with profound changes in mucous production mechanisms
