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Retrieved April 29, 2018

ABCG2 had been shown to pump the dye out of cells, so we knew it must be highly active in these cells and hypothesized that it might also pump the carcinogenic compounds from cigarette smoke out of the cells. To test this hypothesis, the research team inhibited the activity of ABCG2 in the cancer cells in two ways and tested how the cells then reacted to cigarette smoke exposure

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Researchers argue that if future studies continue to find high rates of RYO use and false beliefs around RYO, particularly among youth and young adults, there would be grounds for banning RYO tobacco sales altogether