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In South Korea, NVPs (cigalikes and refillable tank systems) first appeared in 2007 and were advertised as a smoking cessation aid or as a potential alternative to cigarettes 4

In the first direct assessment of brain uptake of nicotine from e-cig use, researchers working on a National Institutes of Health (NIH) grantand one who also accepted a research grant from Juul Labsfound that, yes, e-cigs can deliver nicotine to the brain with similar rapidity as conventional cigarettes

Johns Hopkins Tobacco Treatment Clinic: Obtain a smoking cessation plan that will meet your individual needs