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IBS is a disorder of gut-brain interaction, meaning symptoms are driven by how the gut and brain communicate rather than by structural damage to the gut. This is why a combined approach works best: medications can help manage specific symptoms like diarrhea or cramps, while natural treatments like gut-brain therapy and dietary changes target the underlying gut-brain signaling that keeps symptoms coming back

Horwitz, a professor in the Departments of Population Health and Medicine at NYU Grossman School of Medicine, adds that 60 percent of uninfected participants who did not report olfactory problems also tested poorly during the clinical evaluation

Cannabis binds to CB1 and CB2 cannabinoid receptors, also influencing appetite centers and GI motility, creating potential for additive or unpredictable effects on nausea and digestion