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The reported beneficial effects that nicotine influences in the frontal cortex have been proposed to be largely due to its effects on the 7 nAChR subunit, although there is some evidence surrounding 4b2 receptor subunit activity leading to improved higher cognition (98)

For comparison, direct (nonmodeled) estimates from the National Health Interview Survey (NHIS) [34], a nationally representative household survey, are also plotted

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Therefore, our aim was to establish a cell-based assay that enables us to investigate how smoking affects mitochondrial function in conjunction with HIF signaling in RPE cells
