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[45] Nicotine has potential beneficial effects, but it also has paradoxical effects, which may be due to the inverted U-shape of the dose-response curve or pharmacokinetic features

394 Lesinurad is metabolized and eliminated predominantly by the liver (75%) and to a lesser extent by the kidneys (25%), with a half-life of approximately 9 to 10 h

in geitonogamy, pollen is transferred from the anther of one flower to the stigma of another flower on the same flowering plant, or from microsporangium to ovule within a single (monoecious) gymnosperm

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