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I think there is less nicotine in those products, and they are not combustible, so you are not getting all the particulate matter you get from cigarettes. But, he adds, we are just being very cautious about the long-term consequences of its use

doi: 10.1093/aje/kwn280

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References Atkinson DL, Minnix J, Cinciripini PM, Karam-Hage M