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These promising results should be confirmed by randomized clinical trials that include a long-term follow-up and an evaluation of the impact of the treatment on specific outcomes, such as sustained abstinence, a reduction in the severity of SUDs and the so-called good functioning (i.e., a composite measure encompassing a lack of substance use and no reported legal, psychological, family, or employment problems) [54]

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Metabotropic glutamate receptor antagonists: novel therapeutics for nicotine dependence and depression

Theres like a million things that have to be done