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Smoking rates in the UK have been steadily falling in adults and children, both before and after vapes were introduced

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doi: 10.1002/hep.20907

While it has been proposed that casecontrol studies may underestimate the alcohol-liver cancer association due to pre-existing liver disease, as persons with liver disease may be advised to stop drinking, 11 the positive association between alcohol consumption and liver cancer risk is higher in casecontrol than cohort studies