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Thus if we want to be consistent and relevant to physiological deposition we should adapt the concentration range to the cell model

that would be too obvious

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Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines 31 for each of our systematic reviews, we identified studies reporting relative risk (RR) of incidence or mortality from each of the 36 selected outcomes for smokers compared with nonsmokers

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