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Nicotine may slow gastrointestinal motility (movement), which means things stay in the digestive tract longer and gas may build up

Vane, 1977 Courtesy National Library of Medicine British pharmacologist John Robert Vane (19272004) and Swedish biochemists Sune K

doi: 10.1016/s0015-0282(02)04664-2

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it also promotes platelet-dependent generation of thrombin, a highly potent platelet activator, potentially leading to a positive-feedback loop for platelet activation and coagulation 76)
