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12,16,17 Pharmacists should remind prescribers of the importance of patients being completely opioid-free for 7 to 10 days before initiating therapy with naltrexone, in order to decrease the potential for adverse events

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Lung Cancer 35 , 129136 (2002)
Not only must newcomers compete against long-established international trademarks, but they must also do so in increasingly dark markets
