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In a press release, the company said it would immediately stop accepting orders for the mint-flavored pods from retail partners and stop selling mint-flavored pods online

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Previous studies presented the evidence that CS triggered the acute inflammation via TLR4/MYD88 signaling pathway (2), leading to altered expression of heme oxygenase-1 (HO-1), IL-12, and IL-23 as well as IL-8 ( Figure 2 Taken together, the signaling pathways and molecular mechanisms underlying CS-mediated immunopathology, especially transplant rejection, are still not well understood due to the functional complexity and diversity of cigarette smoke components

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Innovations such as capsule filters in Rothmans or flavored slims in Capri provide customizable experiences, appealing to younger smokers (20-35 years)