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Lucky Strike played up a more innocent side having a teenage girl sing their praises and use remarks like 'Golly!' This fun collection of TV cigarette commercials dates from the 50s through 60s (they were officially banned on January 1, 1971)

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Mutant knockout mouse models also helped to show that nAChRs containing the 5, 3, 2, and 4 subunits are implicated in the somatic manifestations of nicotine withdrawal 108, 109, 146

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