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The agency said it had issued orders for 20 of the products made by the tobacco and nicotine company Swedish Match USA, Inc., "following extensive scientific review." The pouches, including cinnamon, coffee and spearmint flavors, may now be marketed using the risk modification claim that "using ZYN instead of cigarettes puts you at a lower risk of mouth cancer, heart disease, lung cancer, stroke, emphysema and chronic bronchitis." The popular products, which have been authorized for sale in America since January 2025, contain nicotine but don't have tobacco

Soft skin Patients with hEDS likely present with a velvety, silky, soft skin texture and semitransparent skin that causes veins and tendons to be more visible on the forearms (Tinkle et al., 2017), which predispose to skin lesions and lacerations

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doi: 10.1136/jnnp-2012-302414