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But now we have gathered together convincing empirical support for this theory, which can be used to justify new treatment approaches. The study is funded by the National Cancer Institute grant number R01 CA184211 of the National Institutes of Health.

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Proposed benefits: Lobeline may reduce nicotine cravings by occupying acetylcholine receptors without producing full activation, essentially blocking nicotine's rewarding effects.11 This mechanism drove its historical use as a smoking cessation aid among Eclectic physicians