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Nicotine binds specific acetylcholine receptors, mostly neuronal nicotinic acetylcholine receptors (nAChRs) 42 subtypes, in the central nervous system, and stimulates the release of neuromodulators (mainly dopamine) promoting pleasure and thus perpetuating consumption [13]

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However, the impact of smoking on microbial residents of the nasopharyngeal cavity, in contact with cigarette smoke (CS), is lacking

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Receptor levels only returned to normal by 6-12 weeks

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Smoking increases the risk of acute respiratory infections

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