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Patients who had stopped smoking for at least a week by Week 12 (N= 1210) were then randomized to double-blind treatment with CHANTIX (1 mg twice daily) or placebo for an additional 12 weeks and then followed for 28 weeks post-treatment
Of note, there were no significant differences in age at MRI, gender distribution, SES and IQ at age 11 years between the three smoking categories (never smoked, ex-smokers and current smokers), suggesting that the groups were reasonably well matched at baseline
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