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A better understanding of the physiopathogenic mechanisms involved in CR could lead to better treatment for these patients.3,4 OBJECTIVES In the present paper we reviewed the evidence pointing towards the cigarette smoke effects on the respiratory epithelium as well as its role on the pathophysiology of chronic rhinosinusitis

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Replacement Nicotine: a Weapon of Mass Destruction The Gallup Poll also screams the message that three decades of teaching nicotine addicts that nicotine is medicine and its use therapy has cost millions their attempts, and ultimately their lives