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According to the European Pharmacopoeia, there are 7 specified substances the content of which must be test in nicotine

9 Interfere with normal infant lung development (LactMed, 2023)

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Nicotine & Tobacco Research, 15 (1), 231237

Prohibit menthol cigarettes and flavored cigars, as the FDA recently proposed, and strengthen its plan to address the youth e-cigarette epidemic by stopping sales of all flavored e-cigarettes that have not been subject to public health review by the agency