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E-cigarettes gained popularity as they were perceived as a safer option compared to traditional cigarette smoking, which does not involve combustion, the battery-powered devices that create an aerosol for inhalation by heating a material that contains nicotine and frequently other flavours

doi: 10.1001/archpsyc.64.1.76

In addition, urine metabolites of VOCs were creatinine-corrected to obtain covariates adjusted geometric means from the regression models consistent with prior studies using urine biomarkers 9-11

Understanding Commercial Tobacco and Nicotine Products When smoked, tobacco and nicotine products deliver harmful chemicals to the user through inhalation and simultaneously release them into the air