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Candida albicans and Aspergillus fumigatus are commonly detected in CF sputum cultures and have also been associated with acute pulmonary exacerbations [112], and the number of fungal species detected in sputum fluctuated over time [113]

Shulgin, A

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The first was introduced in1988, as Premier, followed by Eclipse from RJ Reynolds Tobacco Company (RJR) and Accord from Phillip Morris International (PMI)

According to the Cancer Research UK and the International Agency for Research on Cancer, cigarettes also contain over 5,000 chemicals (1)
