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doi: 10.1080/14622200802238852
FVC decline was less consistently associated with ILAs across studies, but ILAs that progressed radiologically were associated with a 64-ml annual decline in FVC, compared with a 35-ml decline in those without ILAs (32, 4143) (Table E3)

And the CDC report shows that the problem disproportionately impacts men, American Indians, and costs the country billions each year in health care costs

The methylation levels of 1,405 genes were statistically significantly different among smokers compared with people who had never smoked

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