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Similarly, among current tobacco smokers, e-cigarette smokers, and controls, it was evidenced that urinary excretion of biomarkers of exposure in individuals who ceased regular and electronic cigarette smoking decreased by 6698%, including NNAL (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol), carboxyhemoglobin, nicotine, and its metabolites (52) (Table 3)

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New York has the highest inbound smuggling activity, with an estimated 54.5 percent of cigarettes consumed in the state deriving from smuggled sources in 2021