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This increase in thrombin levels activates several cell-damaging pathways including infiltration of inflammatory cells, proliferation of mesenchymal cells, scar formation, brain edema, seizures, microglial activation, and both astrocytic proliferation and death [19,21,22]

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Nat Protoc 9:15491562 Senthil-Kumar M, Hema R, Anand A, Kang L, Udayakumar M, Mysore KS (2007) A systematic study to determine the extent of gene silencing in Nicotiana benthamiana and other Solanaceae species when heterologous gene sequences are used for virus-induced gene silencing
Adults emerge in late spring, and females often lay a single white egg per bud, rarely 2 eggs per bud when large populations are present
All of these commonly-questioned consequences have been very rare, limited, or entirely nonexistent in prior studies