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Trans - N, N -bis(3,4-dimethoxybenzyl)- N -solanyl 1,2-diaminocyclohexane (N-5228) can also completely reverse the effect of human bladder cancer drug-resistant cell line KK47/TX30 on paclitaxel by mediating p-gp (Enokida et al., 2002)
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Yes smoking reduces lung capacity and lowers oxygen delivery to your muscles, which leads to reduced endurance, quicker fatigue, and poorer overall exercise performance
