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There is spars literature about the effect of nicotine on MS

Two components of counseling are especially effective and clinicians should use these when counseling patients making a quit attempt: Practical counseling (problem-solving/skills training) Social support delivered as part of treatment There are numerous effective medications for tobacco dependence, and clinicians should encourage their use by all patients attempting to quit smoking, except when medically contraindicated or with specific populations for which there is insufficient evidence of effectiveness (i.e., pregnant women, smokeless tobacco users, light smokers, and adolescents)

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A trail of misfortune follows many of the women, including substantial health problems, and although Maddie is quick to believe that this is a coincidence, she inadvertently uncovers evidence that suggests otherwise

If a woman on OCs is trying to quit smoking, the higher stress combined with more intense withdrawal symptoms and nicotine cravings could contribute to lower rates of success