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Global health Price Taxation Disparities Tobacco industry This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial

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The trial is designed to be carried out in 166 clinical investigational sites around the world in at least 3 different continents

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In other words, Massachusetts sacrificed $120 million in annual revenue to have no significant effect on smoking