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Marlboro, its hallmark brand, was seen by many as a cigarette for women an image problem tantamount to suicide in the Don Draper, Frank Sinatra, male-dominated smoking market of postwar America

Nicotine exposure may interfere with the production and regulation of hormones such as testosterone, follicle-stimulating hormone (FSH), and luteinizing hormone (LH), impairing sperm production and maturation

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Plans for a larger-scale phase 3 clinical trial are underway, aiming to build on these promising results and fully elucidate CBDs safety profile for treating dental pain