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The expression of HLA-DR and CD80 in the cell surface of alveolar macrophages (AM) in patients with COPD is decreased compared to smokers with normal lung function and to non-smokers

According to a 2010 study, the nicotine in blunts caused a greater build-up of carbon monoxide, a toxic chemical, in the study subjects' blood, leading to side effects like nausea, dizziness, and headaches

"We are are really hoping that this is a technology that provides a tool that further optimises agriculture so that we are not using outside inputs as much and we are growing more food on less land." However, the authors recognise that using genetic modification is controversial in many parts of the world

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