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FDA also issued a draft concept paper, Illicit Trade in Tobacco Products After Implementation of an FDA Product Standard, which discussed potential illicit trade implications of product standards more generally

Development of tolerance, requiring more nicotine to achieve the same effects

December 1999

For more information regarding nicotine addiction and smoking cessation programs, check out the following resources: Smokefree (smokefree.gov) Quitline (1-800-QUIT-NOW) Centers for Disease Control and Prevention fact sheets on various topics including smoking cessation, health effects of smoking like lung cancer, smokeless tobacco like e-cigarettes

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