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Effect of electronic cigarette aerosol exposure during gestation and lactation on learning and memory of adult male offspring rats

20 Other neurotransmitters that may be involved in nicotine addiction are the hypocretins, neuropeptides produced in the lateral hypothalamus that regulate the stimulatory effects of nicotine on reward centers in the brain and modulate self-administration of nicotine in rodents

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Nrf2 knockout also resulted in further down-regulation of GSH, GCL, l-Glutamic acid and pyroglutamylglycine compared to WT mice (Fig