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According to Prez-Rubio, G.s 2019 study, Role of genetic susceptibility in nicotine addiction and chronic obstructive pulmonary disease., genetic factors contribute to 35% of the risk for nicotine addiction as demonstrated in twin studies

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FDA n.d.) and randomized controlled trials (Faseru et al

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Previous studies have found that tobacco consumption in particular was high across the northeast region, which is corroborated by our findings as well [27,28,29]