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More Resources on Addiction: Nicotine stimulates the release of neurotransmitters such as dopamine, which produce pleasurable sensations and reinforce the desire to use tobacco

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moderate certainty), but may result in little to no harm from other adverse events, such as hiccups, gastrointestinal disturbances, skin irritation from patches, throat irritation, or runny nose.43 Varenicline results in small harms from increases in nausea (32 RCTs, n = 14 963

Secondhand Smoke and Sinus Problems Exposure to secondhand smoke, also known as passive smoking or environmental tobacco smoke, can have detrimental effects on sinus health: Secondhand smoke contains toxins that irritate and inflame sinus tissues, potentially leading to chronic inflammation

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