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The vapor is carbon dioxide, which can displace oxygen and be harmful if inhaled in concentrated amounts

For the study, human corneal tissue was used, and the results were subsequently validated in a classic cell culture model

Clinical Pharmacology and Therapeutics 2012;92(6):7717

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As used by Lasser and colleagues (2000), the term mental illness in this context is defined very broadly to include major depression, bipolar disorder, dysthymia, panic disorder, agoraphobia, social phobia, simple phobia, generalized anxiety disorder, alcohol abuse, alcohol dependence, drug abuse, drug dependence, antisocial personality, conduct disorder, or nonaffective psychosis (Lasser et al