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By the early 1960s, however, Philip Morris scientists had discovered that ammonia could also be used to increase the free nicotine in cigarette smoke, providing a more powerful nicotine kick than the milder low-pH tobaccos traditionally used in American-blend cigarettes

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[DOI] [PMC free article] [PubMed] [Google Scholar] 44.Berros-Crcamo P., Quezada M., Quintanilla M.E., Morales P., Ezquer M., Herrera-Marschitz M., Israel Y., Ezquer F