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Environ Sci Pollut Res 29:4313843151

Read the full article here: Is Smokeless Tobacco Less Harmful to Your Oral Health?

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There is an increase in T-cytotoxic lymphocytes (CD8+) and pro-inflammatory cytokines (TNF- , IL-6, IL-1) and a decrease in CD4+ cells and impaired NK cell activity due to the effect of smoking (Figure 2)
