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Description
Symptoms of Poisoning Ingesting chewing tobacco can cause vomiting, sweating, drowsiness/tiredness, shaking, confusion, seizures and even death

The second, Quitting reduces harm, explained that roll-ups are not less harmful than cigarettes and RYO smoke is toxic, and that quitting reduces harm
About 3-12 hours after ingestion, a person can develop seizures, tremors, rapid shallow breathing, and worsening sleepiness that may progress to coma and death

The reason is twofold

[16] World Health Organisation