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However, in more recent years, the evidence has become more clear: tobacco use is a precipitating factor in migraine attacks

Passive (a.k.a., experimenter-administered) exposure allows for the control of both dose and time of administration relative to other outcome measures (e.g., examination of brain activation after a discrete time period) (60)

[DOI] [PubMed] [Google Scholar] Panagis G, Hildebrand BE, Svensson TH, Nomikos GG

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[ 51 , 52 , 53 , 54 ] Also of note, certain flavors of e-liquid solutions containing diacetyl can cause a disease, bronchiolitis obliterans, commonly referred to as popcorn lung