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[105] Research into nicotine's most predominant metabolite, cotinine, suggests that some, if not most, of nicotine's psychoactive effects may actually be mediated by complex interactions with cotinine, or perhaps even by cotinine alone rather than strictly by nicotine as conventionally thought

"Harm Minimization and Tobacco Control: Reframing Societal Views of Nicotine Use to Rapidly Save Lives"

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With a more extensive investigation, the present work demonstrates that the presence of alcohols in solution has a significant effect on WT-TMV-cp assembly and suggests a mode of action that is relevant to many TMV-cp mutants

Boy Scout troops organized campaigns to paint "Do not Spit on the Sidewalk" notices on city sidewalks