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Non-treatment seeking smokers ( n = 76) were assigned to one of four conditions composed of either a stressful or non-stressful psychosocial challenge followed by either smoking or neutral cues

Nicotine satisfaction is closely related to the protonated and free states of nicotine in the blood ( In conclusion, we observed the pharmacological effects of multiple nicotine salt e-cigarette exposures on brain DA release using animal models that partially simulate human smoking behavior using in vivo fluorescence imaging techniques and found differences in the effects of multiple nicotine salts, providing a new experimental basis for understanding the pharmacological effects of nicotine salts

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[Google Scholar] 46.Snook ME, Severson RF, Arrendale RF, Higman HC, Chortyk OT